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From quiescence to proliferation: Cdk oscillations drive the mammalian cell cycle
We recently proposed a detailed model describing the dynamics of the network of cyclin-dependent kinases (Cdks) driving the mammalian cell cycle (Gérard and Goldbeter, 2009). The model contains four modules, each centered around one cyclin/Cdk complex. Cyclin D/Cdk4–6 and cyclin E/Cdk2 promote progr...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Frontiers Media S.A.
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3487384/ https://ncbi.nlm.nih.gov/pubmed/23130001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2012.00413 |
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