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Histone Deacetylase Activity Selectively Regulates Notch-Mediated Smooth Muscle Differentiation in Human Vascular Cells

BACKGROUND: Histone deacetylases (HDACs) modify smooth muscle cell (SMC) proliferation and affect neointimal lesion formation by regulating cell cycle progression. HDACs might also regulate SMC differentiation, although this is not as well characterized. METHODS AND RESULTS: Notch signaling activate...

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Main Authors: Tang, Yuefeng, Boucher, Joshua M., Liaw, Lucy
格式: Artigo
語言:Inglês
出版: Blackwell Publishing Ltd 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487326/
https://ncbi.nlm.nih.gov/pubmed/23130137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.112.000901
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