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Histone Deacetylase Activity Selectively Regulates Notch-Mediated Smooth Muscle Differentiation in Human Vascular Cells

BACKGROUND: Histone deacetylases (HDACs) modify smooth muscle cell (SMC) proliferation and affect neointimal lesion formation by regulating cell cycle progression. HDACs might also regulate SMC differentiation, although this is not as well characterized. METHODS AND RESULTS: Notch signaling activate...

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Détails bibliographiques
Auteurs principaux: Tang, Yuefeng, Boucher, Joshua M., Liaw, Lucy
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487326/
https://ncbi.nlm.nih.gov/pubmed/23130137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.112.000901
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