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Histone Deacetylase Activity Selectively Regulates Notch-Mediated Smooth Muscle Differentiation in Human Vascular Cells

BACKGROUND: Histone deacetylases (HDACs) modify smooth muscle cell (SMC) proliferation and affect neointimal lesion formation by regulating cell cycle progression. HDACs might also regulate SMC differentiation, although this is not as well characterized. METHODS AND RESULTS: Notch signaling activate...

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Bibliografiske detaljer
Main Authors: Tang, Yuefeng, Boucher, Joshua M., Liaw, Lucy
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487326/
https://ncbi.nlm.nih.gov/pubmed/23130137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.112.000901
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