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Histone Deacetylase Activity Selectively Regulates Notch-Mediated Smooth Muscle Differentiation in Human Vascular Cells

BACKGROUND: Histone deacetylases (HDACs) modify smooth muscle cell (SMC) proliferation and affect neointimal lesion formation by regulating cell cycle progression. HDACs might also regulate SMC differentiation, although this is not as well characterized. METHODS AND RESULTS: Notch signaling activate...

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Detalhes bibliográficos
Main Authors: Tang, Yuefeng, Boucher, Joshua M., Liaw, Lucy
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487326/
https://ncbi.nlm.nih.gov/pubmed/23130137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.112.000901
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