EZH2 mediates epigenetic silencing of neuroblastoma suppressor genes CASZ1, CLU, RUNX3 and NGFR

Neuroblastoma (NB) is the most common extracranial pediatric solid tumor with an undifferentiated status and generally poor prognosis, but the basis for these characteristics remains unknown. In this study, we show that upregulation of the Polycomb complex histone methytransferase EZH2, which limits...

Full description

Saved in:

Bibliographic Details
Main Authors:	Wang, Chunxi, Liu, Zhihui, Woo, Chan-Wook, Li, Zhijie, Wang, Lifeng, Wei, Jun S., Marquez, Victor E., Bates, Susan E., Jin, Qihuang, Khan, Javed, Ge, Kai, Thiele, Carol J.
Format:	Artigo
Language:	Inglês
Published:	2011
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3487161/ https://ncbi.nlm.nih.gov/pubmed/22068036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-0961
Tags:	Add Tag No Tags, Be the first to tag this record!

EZH2 mediates epigenetic silencing of neuroblastoma suppressor genes CASZ1, CLU, RUNX3 and NGFR

Similar Items