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Utilization of Omeprazole To Augment Subtherapeutic Voriconazole Concentrations for Treatment of Aspergillus Infections

Voriconazole is the preferred antifungal agent for Aspergillus infections. Therapeutic drug monitoring is recommended to achieve target concentrations and prevent toxicity. However, variable pharmacokinetics, cytochrome P450 polymorphisms, and extensive drug-drug interactions can contribute to subth...

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Detalhes bibliográficos
Main Authors: Boyd, Natalie K., Zoellner, Cindy L., Swancutt, Mark A., Bhavan, Kavita P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486541/
https://ncbi.nlm.nih.gov/pubmed/22890768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00700-12
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