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Effect of omeprazole on the steady-state pharmacokinetics of voriconazole

AIMS: Voriconazole, a novel triazole antifungal agent, is metabolized by the cytochrome P450 isoenzymes CYP2C19, CYP2C9, and to a lesser extent by CYP3A4. Omeprazole, a proton pump inhibitor used widely for the treatment of gastric and duodenal ulcers, is predominantly metabolized by CYP2C19 and CYP...

詳細記述

保存先:
書誌詳細
主要な著者: Wood, Nolan, Tan, Keith, Purkins, Lynn, Layton, Gary, Hamlin, Julia, Kleinermans, Diane, Nichols, Don
フォーマット: Artigo
言語:Inglês
出版事項: Blackwell Science Inc 2003
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884317/
https://ncbi.nlm.nih.gov/pubmed/14616415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2003.02000.x
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