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The Loss of RGS Protein-Gα(i2) Interactions Results in Markedly Impaired Mouse Neutrophil Trafficking to Inflammatory Sites
Neutrophils are first responders rapidly mobilized to inflammatory sites by a tightly regulated, nonredundant hierarchy of chemoattractants. These chemoattractants engage neutrophil cell surface receptors triggering heterotrimeric G-protein Gα(i) subunits to exchange GDP for GTP. By limiting the dur...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3486189/ https://ncbi.nlm.nih.gov/pubmed/22966200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00651-12 |
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