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Lymph node B lymphocyte trafficking is constrained by anatomy and highly dependent upon chemoattractant desensitization

B lymphocyte recirculation through lymph nodes (LNs) requires crossing endothelial barriers and chemoattractant-triggered cell migration. Here we show how LN anatomy and chemoattractant receptor signaling organize B lymphocyte LN trafficking. Blood-borne B cells predominately used CCR7 signaling to...

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Hlavní autoři: Park, Chung, Hwang, Il-Young, Sinha, Rajesh K., Kamenyeva, Olena, Davis, Michael D., Kehrl, John H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271721/
https://ncbi.nlm.nih.gov/pubmed/22039261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-06-364273
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