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Wnt Antagonist SFRP1 Functions as a Secreted Mediator of Senescence

Cellular senescence has emerged as a critical tumor suppressive mechanism in recent years, but relatively little is known about how senescence occurs. Here, we report that secreted Frizzled-related protein 1 (SFRP1), a secreted antagonist of Wnt signaling, is oversecreted upon cellular senescence ca...

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Bibliografische gegevens
Hoofdauteurs: Elzi, David J., Song, Meihua, Hakala, Kevin, Weintraub, Susan T., Shiio, Yuzuru
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486147/
https://ncbi.nlm.nih.gov/pubmed/22927647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06023-11
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