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Wnt Antagonist SFRP1 Functions as a Secreted Mediator of Senescence
Cellular senescence has emerged as a critical tumor suppressive mechanism in recent years, but relatively little is known about how senescence occurs. Here, we report that secreted Frizzled-related protein 1 (SFRP1), a secreted antagonist of Wnt signaling, is oversecreted upon cellular senescence ca...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3486147/ https://ncbi.nlm.nih.gov/pubmed/22927647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06023-11 |
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