Plasminogen activator inhibitor 1 - insulin-like growth factor binding protein 3 cascade regulates stress-induced senescence

Cellular senescence is widely believed to play a key role in tumor suppression, but the molecular pathways that regulate senescence are only incompletely understood. By using a secretome proteomics approach, we identified insulin-like growth factor binding protein 3 (IGFBP3) as a secreted mediator o...

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Detaylı Bibliyografya
Asıl Yazarlar: Elzi, David J., Lai, Yanlai, Song, Meihua, Hakala, Kevin, Weintraub, Susan T., Shiio, Yuzuru
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2012
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409757/
https://ncbi.nlm.nih.gov/pubmed/22778398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120437109
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