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Alternatively Spliced Telomerase Reverse Transcriptase Variants Lacking Telomerase Activity Stimulate Cell Proliferation

Eight human and six chicken novel alternatively spliced (AS) variants of telomerase reverse transcriptase (TERT) were identified, including a human variant (Δ4-13) containing an in-frame deletion which removed exons 4 through 13, encoding the catalytic domain of telomerase. This variant was expresse...

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Bibliografiske detaljer
Main Authors: Hrdličková, Radmila, Nehyba, Jiří, Bose, Henry R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486134/
https://ncbi.nlm.nih.gov/pubmed/22907755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00550-12
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