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Quantification of Alternative Splicing Variants of Human Telomerase Reverse Transcriptase and Correlations with Telomerase Activity in Lung Cancer

Telomerase plays important roles in the development and progression of malignant tumors, and its activity is primarily determined by transcriptional regulation of human telomerase reverse transcriptase (hTERT). Several mRNA alternative splicing variants (ASVs) for hTERT have been identified, but it...

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Detalhes bibliográficos
Main Authors: Liu, Yan, Wu, Bing-quan, Zhong, Hao-hao, Tian, Xin-xia, Fang, Wei-gang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377688/
https://ncbi.nlm.nih.gov/pubmed/22723897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038868
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