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Quantification of Alternative Splicing Variants of Human Telomerase Reverse Transcriptase and Correlations with Telomerase Activity in Lung Cancer

Telomerase plays important roles in the development and progression of malignant tumors, and its activity is primarily determined by transcriptional regulation of human telomerase reverse transcriptase (hTERT). Several mRNA alternative splicing variants (ASVs) for hTERT have been identified, but it...

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Hlavní autoři: Liu, Yan, Wu, Bing-quan, Zhong, Hao-hao, Tian, Xin-xia, Fang, Wei-gang
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377688/
https://ncbi.nlm.nih.gov/pubmed/22723897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038868
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