Загрузка...

Subtilase Cytotoxin Enhances Escherichia coli Survival in Macrophages by Suppression of Nitric Oxide Production through the Inhibition of NF-κB Activation

Subtilase cytotoxin (SubAB), which is produced by certain strains of Shiga-toxigenic Escherichia coli (STEC), cleaves an endoplasmic reticulum (ER) chaperone, BiP/Grp78, leading to induction of ER stress and caspase-dependent apoptosis. SubAB alters the innate immune response. SubAB pretreatment of...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Tsutsuki, Hiroyasu, Yahiro, Kinnosuke, Suzuki, Kotaro, Suto, Akira, Ogura, Kohei, Nagasawa, Sayaka, Ihara, Hideshi, Shimizu, Takeshi, Nakajima, Hiroshi, Moss, Joel, Noda, Masatoshi
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486033/
https://ncbi.nlm.nih.gov/pubmed/22949549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00581-12
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!