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Pericentromeric Regions Are Refractory To Prompt Repair after Replication Stress-Induced Breakage in HPV16 E6E7-Expressing Epithelial Cells

Chromosomal instability is the major form of genomic instability in cancer cells. Amongst various forms of chromosomal instability, pericentromeric or centromeric instability remains particularly poorly understood. In the present study, we found that pericentromeric instability, evidenced by dynamic...

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Autors principals: Deng, Wen, Tsao, Sai Wah, Guan, Xin-Yuan, Cheung, Annie L. M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485353/
https://ncbi.nlm.nih.gov/pubmed/23119062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048576
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