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Productive Replication of Adeno-Associated Virus Can Occur in Human Papillomavirus Type 16 (HPV-16) Episome-Containing Keratinocytes and Is Augmented by the HPV-16 E2 Protein

We used a sensitive assay to test whether an adeno-associated virus (AAV) productive replication cycle can occur in immortalized human keratinocytes carrying episomal human papillomavirus type 16 (HPV-16) DNA. Following transfection with cloned AAV DNA, infectious AAV was produced, and the infectivi...

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Udgivet i:J Virol
Principais autores: Ogston, Phyllis, Raj, Kenneth, Beard, Peter
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2000
Fag:
Replication
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111857/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10729123/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.8.3494-3504.2000
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