Extremely stringent activation of p16(INK4a) prevents immortalization of uterine cervical epithelial cells without human papillomavirus oncogene expression

Cervical epithelial cell immortalization with defined genetic factors without viral oncogenes has never been reported. Here we report that HPV-negative cervical epithelial cells failed to be immortalized by telomerase activation or the combination of p53 knockdown and telomerase activation. Under th...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Hang, Su, Tiwari, Agnes F.Y., Ngan, Hextan Y.S., Yip, Yim-Ling, Cheung, Annie L.M., Tsao, Sai Wah, Deng, Wen
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216750/
https://ncbi.nlm.nih.gov/pubmed/27344169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10120
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados