Scaffold-Based Pan-Agonist Design for the PPARα, PPARβ and PPARγ Receptors

As important members of nuclear receptor superfamily, Peroxisome proliferator-activated receptors (PPAR) play essential roles in regulating cellular differentiation, development, metabolism, and tumorigenesis of higher organisms. The PPAR receptors have 3 identified subtypes: PPARα, PPARβ and PPARγ,...

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Autores principales: Zhang, Li-Song, Wang, Shu-Qing, Xu, Wei-Ren, Wang, Run-Ling, Wang, Jing-Fang
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485212/
https://ncbi.nlm.nih.gov/pubmed/23119024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048453
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