Comparative Gene Expression Profiles Induced by PPARγ and PPARα/γ Agonists in Human Hepatocytes

BACKGROUND: Several glitazones (PPARγ agonists) and glitazars (dual PPARα/γ agonists) have been developed to treat hyperglycemia and, simultaneously, hyperglycemia and dyslipidemia, respectively. However, most have caused idiosyncratic hepatic or extrahepatic toxicities through mechanisms that remai...

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Detaylı Bibliyografya
Asıl Yazarlar: Rogue, Alexandra, Lambert, Carine, Jossé, Rozenn, Antherieu, Sebastien, Spire, Catherine, Claude, Nancy, Guillouzo, André
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2011
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078935/
https://ncbi.nlm.nih.gov/pubmed/21533120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018816
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