A Δ38 Deletion Variant of Human Transketolase as a Model of Transketolase-Like Protein 1 Exhibits No Enzymatic Activity

Besides transketolase (TKT), a thiamin-dependent enzyme of the pentose phosphate pathway, the human genome encodes for two closely related transketolase-like proteins, which share a high sequence identity with TKT. Transketolase-like protein 1 (TKTL1) has been implicated in cancerogenesis as its cel...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Schneider, Stefan, Lüdtke, Stefan, Schröder-Tittmann, Kathrin, Wechsler, Cindy, Meyer, Danilo, Tittmann, Kai
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485151/
https://ncbi.nlm.nih.gov/pubmed/23118983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048321
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