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The Crystal Structure of Human Transketolase and New Insights into Its Mode of Action
The crystal structure of human transketolase (TKT), a thiamine diphosphate (ThDP) and Ca(2+)-dependent enzyme that catalyzes the interketol transfer between ketoses and aldoses as part of the pentose phosphate pathway, has been determined to 1.75 Å resolution. The recombinantly produced protein crys...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2951230/ https://ncbi.nlm.nih.gov/pubmed/20667822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.149955 |
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