The Crystal Structure of Human Transketolase and New Insights into Its Mode of Action

The crystal structure of human transketolase (TKT), a thiamine diphosphate (ThDP) and Ca(2+)-dependent enzyme that catalyzes the interketol transfer between ketoses and aldoses as part of the pentose phosphate pathway, has been determined to 1.75 Å resolution. The recombinantly produced protein crys...

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Hlavní autoři: Mitschke, Lars, Parthier, Christoph, Schröder-Tittmann, Kathrin, Coy, Johannes, Lüdtke, Stefan, Tittmann, Kai
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
Enzymology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951230/
https://ncbi.nlm.nih.gov/pubmed/20667822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.149955
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