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2-Hydroxyoleic Acid Induces ER Stress and Autophagy in Various Human Glioma Cell Lines

BACKGROUND: 2-Hydroxyoleic acid is a synthetic fatty acid with potent anti-cancer activity which does not induce undesired side effects. However, the molecular and cellular mechanisms by which this compound selectively kills human glioma cancer cells without killing normal cells is not fully underst...

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Detalhes bibliográficos
Main Authors: Marcilla-Etxenike, Amaia, Martín, Maria Laura, Noguera-Salvà, Maria Antònia, García-Verdugo, José Manuel, Soriano-Navarro, Mario, Dey, Indranil, Escribá, Pablo V., Busquets, Xavier
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484997/
https://ncbi.nlm.nih.gov/pubmed/23133576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048235
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