2-Hydroxyoleate, a nontoxic membrane binding anticancer drug, induces glioma cell differentiation and autophagy

Despite recent advances in the development of new cancer therapies, the treatment options for glioma remain limited, and the survival rate of patients has changed little over the past three decades. Here, we show that 2-hydroxyoleic acid (2OHOA) induces differentiation and autophagy of human glioma...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Terés, Silvia, Lladó, Victoria, Higuera, Mónica, Barceló-Coblijn, Gwendolyn, Martin, Maria Laura, Noguera-Salvà, Maria Antònia, Marcilla-Etxenike, Amaia, García-Verdugo, José Manuel, Soriano-Navarro, Mario, Saus, Carlos, Gómez-Pinedo, Ulises, Busquets, Xavier, Escribá, Pablo V.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2012
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365159/
https://ncbi.nlm.nih.gov/pubmed/22586083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118349109
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