2-Hydroxyoleate, a nontoxic membrane binding anticancer drug, induces glioma cell differentiation and autophagy

Despite recent advances in the development of new cancer therapies, the treatment options for glioma remain limited, and the survival rate of patients has changed little over the past three decades. Here, we show that 2-hydroxyoleic acid (2OHOA) induces differentiation and autophagy of human glioma...

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Main Authors: Terés, Silvia, Lladó, Victoria, Higuera, Mónica, Barceló-Coblijn, Gwendolyn, Martin, Maria Laura, Noguera-Salvà, Maria Antònia, Marcilla-Etxenike, Amaia, García-Verdugo, José Manuel, Soriano-Navarro, Mario, Saus, Carlos, Gómez-Pinedo, Ulises, Busquets, Xavier, Escribá, Pablo V.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2012
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365159/
https://ncbi.nlm.nih.gov/pubmed/22586083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118349109
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