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Pivotal role of dihydrofolate reductase knockdown in the anticancer activity of 2-hydroxyoleic acid
α-Hydroxy-9-cis-octadecenoic acid, a synthetic fatty acid that modifies the composition and structure of lipid membranes. 2-Hydroxyoleic acid (HOA) generated interest due to its potent, yet nontoxic, anticancer activity. It induces cell cycle arrest in human lung cancer (A549) cells and apoptosis in...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2720411/ https://ncbi.nlm.nih.gov/pubmed/19666584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907300106 |
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