PSD-95 expression controls l-DOPA dyskinesia through dopamine D1 receptor trafficking

l-DOPA–induced dyskinesia (LID), a detrimental consequence of dopamine replacement therapy for Parkinson’s disease, is associated with an alteration in dopamine D1 receptor (D1R) and glutamate receptor interactions. We hypothesized that the synaptic scaffolding protein PSD-95 plays a pivotal role in...

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Bibliografische gegevens
Hoofdauteurs: Porras, Gregory, Berthet, Amandine, Dehay, Benjamin, Li, Qin, Ladepeche, Laurent, Normand, Elisabeth, Dovero, Sandra, Martinez, Audrey, Doudnikoff, Evelyne, Martin-Négrier, Marie-Laure, Chuan, Qin, Bloch, Bertrand, Choquet, Daniel, Boué-Grabot, Eric, Groc, Laurent, Bezard, Erwan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2012
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484432/
https://ncbi.nlm.nih.gov/pubmed/23041629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI59426
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