PSD-95 expression controls l-DOPA dyskinesia through dopamine D1 receptor trafficking

l-DOPA–induced dyskinesia (LID), a detrimental consequence of dopamine replacement therapy for Parkinson’s disease, is associated with an alteration in dopamine D1 receptor (D1R) and glutamate receptor interactions. We hypothesized that the synaptic scaffolding protein PSD-95 plays a pivotal role in...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Porras, Gregory, Berthet, Amandine, Dehay, Benjamin, Li, Qin, Ladepeche, Laurent, Normand, Elisabeth, Dovero, Sandra, Martinez, Audrey, Doudnikoff, Evelyne, Martin-Négrier, Marie-Laure, Chuan, Qin, Bloch, Bertrand, Choquet, Daniel, Boué-Grabot, Eric, Groc, Laurent, Bezard, Erwan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2012
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484432/
https://ncbi.nlm.nih.gov/pubmed/23041629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI59426
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