PSD-95 expression controls l-DOPA dyskinesia through dopamine D1 receptor trafficking

l-DOPA–induced dyskinesia (LID), a detrimental consequence of dopamine replacement therapy for Parkinson’s disease, is associated with an alteration in dopamine D1 receptor (D1R) and glutamate receptor interactions. We hypothesized that the synaptic scaffolding protein PSD-95 plays a pivotal role in...

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Detalhes bibliográficos
Main Authors: Porras, Gregory, Berthet, Amandine, Dehay, Benjamin, Li, Qin, Ladepeche, Laurent, Normand, Elisabeth, Dovero, Sandra, Martinez, Audrey, Doudnikoff, Evelyne, Martin-Négrier, Marie-Laure, Chuan, Qin, Bloch, Bertrand, Choquet, Daniel, Boué-Grabot, Eric, Groc, Laurent, Bezard, Erwan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484432/
https://ncbi.nlm.nih.gov/pubmed/23041629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI59426
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