PSD-95 expression controls l-DOPA dyskinesia through dopamine D1 receptor trafficking

l-DOPA–induced dyskinesia (LID), a detrimental consequence of dopamine replacement therapy for Parkinson’s disease, is associated with an alteration in dopamine D1 receptor (D1R) and glutamate receptor interactions. We hypothesized that the synaptic scaffolding protein PSD-95 plays a pivotal role in...

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Main Authors: Porras, Gregory, Berthet, Amandine, Dehay, Benjamin, Li, Qin, Ladepeche, Laurent, Normand, Elisabeth, Dovero, Sandra, Martinez, Audrey, Doudnikoff, Evelyne, Martin-Négrier, Marie-Laure, Chuan, Qin, Bloch, Bertrand, Choquet, Daniel, Boué-Grabot, Eric, Groc, Laurent, Bezard, Erwan
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2012
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484432/
https://ncbi.nlm.nih.gov/pubmed/23041629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI59426
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