Defining a Gene Promoter Methylation Signature in Sputum for Lung Cancer Risk Assessment

PURPOSE: To evaluate the methylation state of 31 genes in sputum as biomarkers in an expanded nested, case-control study from the Colorado Cohort and to assess the replication of results from the most promising genes in an independent case-control study of asymptomatic Stage I lung cancer patients f...

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Autori principali: Leng, Shuguang, Do, Kieu, Yingling, Christin M., Picchi, Maria A., Wolf, Holly J., Kennedy, Timothy C., Feser, William J., Baron, Anna E., Franklin, Wilbur A., Brock, Malcolm V., Herman, James G., Baylin, Stephen B., Byers, Tim, Stidley, Christine A., Belinsky, Steven A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483793/
https://ncbi.nlm.nih.gov/pubmed/22510351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-3049
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