Quantitative Longitudinal Imaging of Vascular Inflammation and Treatment by Ezetimibe in apoE Mice by FMT Using New Optical Imaging Biomarkers of Cathepsin Activity and α (v) β (3) Integrin

Inflammation as a core pathological event of atherosclerotic lesions is associated with the secretion of cathepsin proteases and the expression of α (v) β (3) integrin. We employed fluorescence molecular tomographic (FMT) noninvasive imaging of these molecular activities using cathepsin sensing (Pro...

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Main Authors: Lin, Shu-An, Patel, Manishkumar, Suresch, Donna, Connolly, Brett, Bao, Bagna, Groves, Kevin, Rajopadhye, Milind, Peterson, Jeffrey D., Klimas, Michael, Sur, Cyrille, Bednar, Bohumil
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483711/
https://ncbi.nlm.nih.gov/pubmed/23119157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/189254
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