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Hybrid in vivo FMT-CT imaging of protease activity in atherosclerosis with customized nanosensors

OBJECTIVE: Proteases are emerging biomarkers of inflammatory diseases. In atherosclerosis, these enzymes are often secreted by inflammatory macrophages, digest the extracellular matrix of the fibrous cap and destabilize atheromata. Protease function can be monitored with protease activatable imaging...

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Detalhes bibliográficos
Main Authors: Nahrendorf, Matthias, Waterman, Peter, Thurber, Greg, Groves, Kevin, Rajopadhye, Milind, Panizzi, Peter, Marinelli, Brett, Aikawa, Elena, Pittet, Mikael J, Swirski, Filip K, Weissleder, Ralph
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746251/
https://ncbi.nlm.nih.gov/pubmed/19608968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.109.193086
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