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Nanoparticle PET-CT imaging of macrophages in inflammatory atherosclerosis

BACKGROUND: Macrophages (Mø) participate centrally in atherosclerosis and Mø markers (e.g. CD68, MAC-3) correlate well with lesion severity and therapeutic modulation. Based on the avidity of lesional Mø for polysaccharide containing supramolecular structures such as nanoparticles, we have developed...

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Bibliographic Details
Main Authors: Nahrendorf, Matthias, Zhang, Hanwen, Hembrador, Sheena, Panizzi, Peter, Sosnovik, David E., Aikawa, Elena, Libby, Peter, Swirski, Filip K., Weissleder, Ralph
Format: Artigo
Language:Inglês
Published: 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663426/
https://ncbi.nlm.nih.gov/pubmed/18158358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.107.741181
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