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(18)F-4V for PET-CT imaging of VCAM-1 expression in inflammatory atherosclerosis

OBJECTIVES: To iteratively develope and validate an (18)F labeled small molecule VCAM-1 affinity ligand and demonstrate the feasibility of imaging VCAM-1 expression by PET-CT in murine arteries. BACKGROUND: Hybrid PET-CT imaging may allow simultaneous assessment of atherosclerotic lesion morphology...

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Main Authors: Nahrendorf, Matthias, Keliher, Edmund, Panizzi, Peter, Zhang, Hanwen, Hembrador, Sheena, Figueiredo, Jose-Luiz, Aikawa, Elena, Kelly, Kimberly, Libby, Peter, Weissleder, Ralph
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773129/
https://ncbi.nlm.nih.gov/pubmed/19833312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmg.2009.04.016
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