A fluorogenic near-infrared imaging agent for quantifying plasma and local tissue renin activity in vivo and ex vivo

The renin-angiotensin system (RAS) is well studied for its regulation of blood pressure and fluid homeostasis, as well as for increased activity associated with a variety of diseases and conditions, including cardiovascular disease, diabetes, and kidney disease. The enzyme renin cleaves angiotensino...

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Detalhes bibliográficos
Main Authors: Zhang, Jun, Preda, Dorin V., Vasquez, Kristine O., Morin, Jeff, Delaney, Jeannine, Bao, Bagna, Percival, M. David, Xu, Daigen, McKay, Dan, Klimas, Michael, Bednar, Bohumil, Sur, Cyrille, Gao, David Z., Madden, Karen, Yared, Wael, Rajopadhye, Milind, Peterson, Jeffrey D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Innovative Methodology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423114/
https://ncbi.nlm.nih.gov/pubmed/22674025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00361.2011
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