Noninvasive In Vivo Quantification of Neutrophil Elastase Activity in Acute Experimental Mouse Lung Injury

We developed a neutrophil elastase-specific near-infrared fluorescence imaging agent, which, combined with fluorescence molecular tomographic imaging, allowed us to detect and quantify neutrophil elastase activity in vivo, in real time, and noninvasively in an acute model of lung injury (ALI). Signi...

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Hauptverfasser: Kossodo, Sylvie, Zhang, Jun, Groves, Kevin, Cuneo, Garry J., Handy, Emma, Morin, Jeff, Delaney, Jeannine, Yared, Wael, Rajopadhye, Milind, Peterson, Jeffrey D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175392/
https://ncbi.nlm.nih.gov/pubmed/21941648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/581406
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