Noninvasive In Vivo Quantification of Neutrophil Elastase Activity in Acute Experimental Mouse Lung Injury

We developed a neutrophil elastase-specific near-infrared fluorescence imaging agent, which, combined with fluorescence molecular tomographic imaging, allowed us to detect and quantify neutrophil elastase activity in vivo, in real time, and noninvasively in an acute model of lung injury (ALI). Signi...

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Detalhes bibliográficos
Main Authors: Kossodo, Sylvie, Zhang, Jun, Groves, Kevin, Cuneo, Garry J., Handy, Emma, Morin, Jeff, Delaney, Jeannine, Yared, Wael, Rajopadhye, Milind, Peterson, Jeffrey D.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175392/
https://ncbi.nlm.nih.gov/pubmed/21941648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/581406
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