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MEK is a key regulator of gliogenesis in the developing brain

We have defined functions of MEK in regulating gliogenesis in developing cerebral cortex using loss and gain of function mouse genetics. Radial progenitors deficient in both Mek1 and Mek2 fail to transition to the gliogenic mode in late embryogenesis, and astrocyte and oligodendroglial precursors fa...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Li, Xiaoyan, Newbern, Jason, Wu, Yaohong, Morgan-Smith, Meghan, Zhong, Jian, Charron, Jean, Snider, William
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483643/
https://ncbi.nlm.nih.gov/pubmed/22998872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2012.08.031
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