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Specific functions for ERK/MAPK signaling during PNS development

We have established functions of the stimulus dependent MAPKs, ERK1/2 and ERK5 in DRG, motor neuron, and Schwann cell development. Surprisingly, many aspects of early DRG and motor neuron development were found to be ERK1/2 independent and Erk5 deletion had no obvious effect on embryonic PNS. In con...

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Detalhes bibliográficos
Main Authors: Newbern, Jason M., Li, Xiaoyan, Shoemaker, Sarah E., Zhou, Jiang, Zhong, Jian, Wu, Yaohong, Bonder, Daniel, Hollenback, Steven, Coppola, Giovanni, Geschwind, Daniel H., Landreth, Gary E., Snider, William D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060558/
https://ncbi.nlm.nih.gov/pubmed/21220101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2010.12.003
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