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MEK is a key regulator of gliogenesis in the developing brain
We have defined functions of MEK in regulating gliogenesis in developing cerebral cortex using loss and gain of function mouse genetics. Radial progenitors deficient in both Mek1 and Mek2 fail to transition to the gliogenic mode in late embryogenesis, and astrocyte and oligodendroglial precursors fa...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3483643/ https://ncbi.nlm.nih.gov/pubmed/22998872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2012.08.031 |
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