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GSK-3 signaling in developing cortical neurons is essential for radial migration and dendritic orientation
GSK-3 is an essential mediator of several signaling pathways that regulate cortical development. We therefore created conditional mouse mutants lacking both GSK-3α and GSK-3β in newly born cortical excitatory neurons. Gsk3-deleted neurons expressing upper layer markers exhibited striking migration f...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
eLife Sciences Publications, Ltd
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4109311/ https://ncbi.nlm.nih.gov/pubmed/25073924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02663 |
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