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Systematic elucidation and in vivo validation of sequences enriched in hindbrain transcriptional control

Illuminating the primary sequence encryption of enhancers is central to understanding the regulatory architecture of genomes. We have developed a machine learning approach to decipher motif patterns of hindbrain enhancers and identify 40,000 sequences in the human genome that we predict display regu...

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Bibliografske podrobnosti
Main Authors: Burzynski, Grzegorz M., Reed, Xylena, Taher, Leila, Stine, Zachary E., Matsui, Takeshi, Ovcharenko, Ivan, McCallion, Andrew S.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483557/
https://ncbi.nlm.nih.gov/pubmed/22759862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.139717.112
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