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Systematic elucidation and in vivo validation of sequences enriched in hindbrain transcriptional control

Illuminating the primary sequence encryption of enhancers is central to understanding the regulatory architecture of genomes. We have developed a machine learning approach to decipher motif patterns of hindbrain enhancers and identify 40,000 sequences in the human genome that we predict display regu...

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Detalhes bibliográficos
Main Authors: Burzynski, Grzegorz M., Reed, Xylena, Taher, Leila, Stine, Zachary E., Matsui, Takeshi, Ovcharenko, Ivan, McCallion, Andrew S.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483557/
https://ncbi.nlm.nih.gov/pubmed/22759862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.139717.112
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