Genome-wide identification of conserved regulatory function in diverged sequences

Plasticity of gene regulatory encryption can permit DNA sequence divergence without loss of function. Functional information is preserved through conservation of the composition of transcription factor binding sites (TFBS) in a regulatory element. We have developed a method that can accurately ident...

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Detalhes bibliográficos
Main Authors: Taher, Leila, McGaughey, David M., Maragh, Samantha, Aneas, Ivy, Bessling, Seneca L., Miller, Webb, Nobrega, Marcelo A., McCallion, Andrew S., Ovcharenko, Ivan
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129256/
https://ncbi.nlm.nih.gov/pubmed/21628450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.119016.110
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