Genome-wide identification of conserved regulatory function in diverged sequences

Plasticity of gene regulatory encryption can permit DNA sequence divergence without loss of function. Functional information is preserved through conservation of the composition of transcription factor binding sites (TFBS) in a regulatory element. We have developed a method that can accurately ident...

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Autors principals: Taher, Leila, McGaughey, David M., Maragh, Samantha, Aneas, Ivy, Bessling, Seneca L., Miller, Webb, Nobrega, Marcelo A., McCallion, Andrew S., Ovcharenko, Ivan
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2011
Matèries:
Method
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129256/
https://ncbi.nlm.nih.gov/pubmed/21628450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.119016.110
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