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Steroid hormone modulation of RET through two estrogen responsive enhancers in breast cancer
RET, a gene causatively mutated in Hirschsprung disease and cancer, has recently been implicated in breast cancer estrogen (E2) independence and tamoxifen resistance. RET displays both E2 and retinoic acid (RA)-dependent transcriptional modulation in E2-responsive breast cancers. However, the regula...
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Autores principales: | , , , , |
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Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3168285/ https://ncbi.nlm.nih.gov/pubmed/21737465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr291 |
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