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Phenotype variation in two-locus mouse models of Hirschsprung disease: Tissue-specific interaction between Ret and Ednrb

Clinical expression of Hirschsprung disease (HSCR) requires the interaction of multiple susceptibility genes. Molecular genetic analyses have revealed that interactions between mutations in the genes encoding the RET receptor tyrosine kinase and the endothelin receptor type B (EDNRB) are central to...

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Main Authors: McCallion, Andrew S., Stames, Erine, Conlon, Ronald A., Chakravarti, Aravinda
Formáid: Artigo
Teanga:Inglês
Foilsithe: The National Academy of Sciences 2003
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC149918/
https://ncbi.nlm.nih.gov/pubmed/12574515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0337540100
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