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Phenotype variation in two-locus mouse models of Hirschsprung disease: Tissue-specific interaction between Ret and Ednrb

Clinical expression of Hirschsprung disease (HSCR) requires the interaction of multiple susceptibility genes. Molecular genetic analyses have revealed that interactions between mutations in the genes encoding the RET receptor tyrosine kinase and the endothelin receptor type B (EDNRB) are central to...

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Autors principals: McCallion, Andrew S., Stames, Erine, Conlon, Ronald A., Chakravarti, Aravinda
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC149918/
https://ncbi.nlm.nih.gov/pubmed/12574515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0337540100
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