Genome-wide identification of conserved regulatory function in diverged sequences

Plasticity of gene regulatory encryption can permit DNA sequence divergence without loss of function. Functional information is preserved through conservation of the composition of transcription factor binding sites (TFBS) in a regulatory element. We have developed a method that can accurately ident...

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Bibliographische Detailangaben
Hauptverfasser: Taher, Leila, McGaughey, David M., Maragh, Samantha, Aneas, Ivy, Bessling, Seneca L., Miller, Webb, Nobrega, Marcelo A., McCallion, Andrew S., Ovcharenko, Ivan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2011
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Method
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129256/
https://ncbi.nlm.nih.gov/pubmed/21628450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.119016.110
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